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thewayneThe numbers are very indicative in multiple studies, but the mechanism is unclear.
The current vaccine is two-fold. There's the direct chicken pox vaccine to suppress that particular disease. A second adjuvant is designed to stimulate the immune system to provide a vigorous response if the chicken pox reactivates. It's believed that this adjuvant is acting as a strong anti-inflammatory and this might be reducing people contracting dementia.
The papers cited, from across several countries, all show interesting numbers. I'd like to see a meta-study to try to establish stronger numbers. Interestingly, women show the most benefit from this effect, but also are more likely to contract shingles and are more likely to develop dementia.
I saw another article recently that talked about people who get cancer rarely develop dementia, though I didn't dig into that one as I've had several relatives and friends with both, and it hit a little too close to home.
As always, no vaccine is absolute proof against a disease, these studies show a 5-20%+ reduction in the chance of developing dementia, not absolute resistance. Still, that's encouraging, and if the mechanism can be understood, it could lead to the development of a vaccine to further improve resistance against dementia.
https://arstechnica.com/health/2026/02/could-a-vaccine-prevent-dementia-shingles-shot-data-only-getting-stronger/
The current vaccine is two-fold. There's the direct chicken pox vaccine to suppress that particular disease. A second adjuvant is designed to stimulate the immune system to provide a vigorous response if the chicken pox reactivates. It's believed that this adjuvant is acting as a strong anti-inflammatory and this might be reducing people contracting dementia.
The papers cited, from across several countries, all show interesting numbers. I'd like to see a meta-study to try to establish stronger numbers. Interestingly, women show the most benefit from this effect, but also are more likely to contract shingles and are more likely to develop dementia.
I saw another article recently that talked about people who get cancer rarely develop dementia, though I didn't dig into that one as I've had several relatives and friends with both, and it hit a little too close to home.
As always, no vaccine is absolute proof against a disease, these studies show a 5-20%+ reduction in the chance of developing dementia, not absolute resistance. Still, that's encouraging, and if the mechanism can be understood, it could lead to the development of a vaccine to further improve resistance against dementia.
https://arstechnica.com/health/2026/02/could-a-vaccine-prevent-dementia-shingles-shot-data-only-getting-stronger/
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Date: 2026-02-26 10:18 pm (UTC)There are also reports that HRT protects against dementia too.
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Date: 2026-02-27 12:19 am (UTC)Got my shots a couple of years back.
WORST vaccinations I have ever got. LOL........
Hugs, Jon
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Date: 2026-02-27 01:44 am (UTC)I guess he who shall not be named, aka asshole, should have taken the jab!
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Date: 2026-02-27 01:46 am (UTC)no subject
Date: 2026-02-27 02:10 am (UTC)They both hit me kind of hard.
After the second I thought WOW...
Only to realize, it was partly the shot and partly that I had caught Covid. lol... :o
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Date: 2026-02-27 03:35 am (UTC)no subject
Date: 2026-02-27 05:29 am (UTC)I didn't have a problem with the first, but as I recall the second one hurt for a few days.
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Date: 2026-02-27 05:30 am (UTC)Oh, man! That sucks!
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Date: 2026-02-27 05:33 am (UTC)Yeah, kind of in the realm of causation vs correlation. Maybe there was a relationship, maybe the dementia was already building and just tipped over into something more visible, or possibly she had a micro-stroke that caused the dementia to leap to the forefront. Very hard to say. I remember reading an MRI report on my dad about a decade ago reporting on 'multiple micro-strokes', and there was no evidence of impairment that I could see about him. My brother swore he had dementia, he possibly had Sundowners at the end, I never saw it though, but the last time I saw him before his death was a couple of weeks and he wasn't in good shape with his cancers.