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thewayneNot exactly something you want to see in a vaccine!
From the article:
"The (vaccine's) molecular clamp is made from a HIV protein, which on its own is harmless. The molecular clamp stabilizes the coronavirus spike protein and presents it to the body in a way that promotes a good immune response. This is why the clamp technology is so vital," Taylor said.
He added that the clamp model vaccine had shown "good safety and immune response" against the coronavirus in early clinical trials, and the possibility for generating an HIV positive result had been thought to be low.
Yeah. Apparently not as low as they'd thought!
https://www.cnn.com/2020/12/10/australia/australia-vaccine-hiv-intl-hnk/index.html
From the article:
"The (vaccine's) molecular clamp is made from a HIV protein, which on its own is harmless. The molecular clamp stabilizes the coronavirus spike protein and presents it to the body in a way that promotes a good immune response. This is why the clamp technology is so vital," Taylor said.
He added that the clamp model vaccine had shown "good safety and immune response" against the coronavirus in early clinical trials, and the possibility for generating an HIV positive result had been thought to be low.
Yeah. Apparently not as low as they'd thought!
https://www.cnn.com/2020/12/10/australia/australia-vaccine-hiv-intl-hnk/index.html
no subject
Date: 2020-12-12 07:42 pm (UTC)It's a novel and interesting approach -- stick a molecular clamp on the virus' spike protein to prevent it from binding -- but REALLY new, even newer than the MRNA approaches.
The traditional inactive-virus vaccines are having trouble being effective enough; the Oxford trail has a huge spread of effectivenesses for the 95% confidence interval. They're trying for a mix, or a sequence of shots, to get a sufficient overall effect. It's going to take several really big trails, because it's pretty likely dosage and order and spacing all matter.