The study concerned a "sugar alcohol" that is commonly used in keto-friendly foods as a sugar replacement, and found some nastiness associated with it. It was a small study, with only 20 people enrolled, but the results were telling, the phrase "worrisome cardiovascular effects" is mentioned..
"Earlier studies from Hazen’s lab — one published last year and the other in June — found potential links between the sugar alcohols and an increased risk of heart attacks and strokes. The research suggested both sugar alcohols might make blood platelets stickier and therefore more susceptible to clotting and blocking veins or arteries, in turn contributing to heart attacks and strokes.
For the new research, Hazen’s team analyzed the heart effects of erythritol and regular sugar — in this case, simple glucose — by enrolling two groups of healthy middle-aged male and female volunteers: 10 who consumed the erythritol and 10 who consumed sugar.
Both groups fasted overnight. In the morning, their blood was drawn to measure platelet activity. Then, half the volunteers drank glasses of water with 30 grams of glucose mixed in, and half drank glasses of water with 30 grams of erythritol. Hazen said 30 grams of erythritol is an amount typical of erythritol-sweetened foods.
Around 30 minutes after each group consumed the sweetened drinks, their blood was drawn and retested. Researchers found the people who consumed erythritol had increased platelet aggregation — meaning the blood was more likely to clot. Adults who drank the normal sugar drink had no changes in platelet aggregation.
The researchers measured a 1,000-fold increase in blood erythritol levels in the group given the erythritol drink. Those who drank glucose water didn’t have any changes in blood erythritol levels, and their blood glucose levels were only slightly increased. The finding stood out to Hazen, because it far exceeded the trace levels of erythritol that occur naturally in the blood.
“The amount in sugar substitutes is thousands of folds higher than what is made in our bodies, so to call it ‘natural,’ it’s not,” he said. “Your best recommendation is to avoid the sugar substitutes, and sugar alcohols in particular, because there’s an acute increase in the likelihood of clotting events once you ingest them.”
Obviously if you're diabetic, you have special concerns. Myself, I avoid artificial sweeteners and don't use a lot of sugar. Yes, I make ice cream, but only once or twice a month. I don't make other types of desserts very often either.
https://www.nbcnews.com/health/heart-health/common-low-calorie-sweetener-may-riskier-heart-sugar-study-suggests-rcna165655
https://science.slashdot.org/story/24/08/08/1748237/common-low-calorie-sweetener-may-be-riskier-for-the-heart-than-sugar-study-suggests
"Earlier studies from Hazen’s lab — one published last year and the other in June — found potential links between the sugar alcohols and an increased risk of heart attacks and strokes. The research suggested both sugar alcohols might make blood platelets stickier and therefore more susceptible to clotting and blocking veins or arteries, in turn contributing to heart attacks and strokes.
For the new research, Hazen’s team analyzed the heart effects of erythritol and regular sugar — in this case, simple glucose — by enrolling two groups of healthy middle-aged male and female volunteers: 10 who consumed the erythritol and 10 who consumed sugar.
Both groups fasted overnight. In the morning, their blood was drawn to measure platelet activity. Then, half the volunteers drank glasses of water with 30 grams of glucose mixed in, and half drank glasses of water with 30 grams of erythritol. Hazen said 30 grams of erythritol is an amount typical of erythritol-sweetened foods.
Around 30 minutes after each group consumed the sweetened drinks, their blood was drawn and retested. Researchers found the people who consumed erythritol had increased platelet aggregation — meaning the blood was more likely to clot. Adults who drank the normal sugar drink had no changes in platelet aggregation.
The researchers measured a 1,000-fold increase in blood erythritol levels in the group given the erythritol drink. Those who drank glucose water didn’t have any changes in blood erythritol levels, and their blood glucose levels were only slightly increased. The finding stood out to Hazen, because it far exceeded the trace levels of erythritol that occur naturally in the blood.
“The amount in sugar substitutes is thousands of folds higher than what is made in our bodies, so to call it ‘natural,’ it’s not,” he said. “Your best recommendation is to avoid the sugar substitutes, and sugar alcohols in particular, because there’s an acute increase in the likelihood of clotting events once you ingest them.”
Obviously if you're diabetic, you have special concerns. Myself, I avoid artificial sweeteners and don't use a lot of sugar. Yes, I make ice cream, but only once or twice a month. I don't make other types of desserts very often either.
https://www.nbcnews.com/health/heart-health/common-low-calorie-sweetener-may-riskier-heart-sugar-study-suggests-rcna165655
https://science.slashdot.org/story/24/08/08/1748237/common-low-calorie-sweetener-may-be-riskier-for-the-heart-than-sugar-study-suggests